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Updated: Jan 14, 2026

A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization
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A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization

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F. rodentium Cas9 的结构和功能基础为CRISPR-Cas蛋白质工程提供了洞察力

Mei Yang1, Siqi Liu2, Guanqiao Chen3

  • 1Department of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, Guangdong, China; Molecular Imaging Center, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, Guangdong, China; Guangdong-Hong Kong-Macao University Joint Laboratory of Interventional Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, Guangdong, China.

Cell genomics
|October 17, 2025
PubMed
概括

在Faecalibaculum动物Cas9 (FrCas9) 系统提供卓越的基因编辑精度. 结构和突变研究揭示了提高效率和减少目标外影响的机制,为先进的CRISPR技术铺平了道路.

关键词:
这就是CRISPR-Cas.这就是Cas9的情况.化-EM结构的结构.工程 工程 工程 工程 工程高保真度的高保真度可以使用.酸锁环的使用方法

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