关于艾滋病毒人口中外周动脉疾病的疾病风险和当代管理的审查
Michael C Wilkinson1, Roy O Mathew2, Sharon C Kiang3
1Division of Vascular Surgery, Department of Surgery, Loma Linda University Health, Loma Linda, CA.
Annals of vascular surgery
|October 17, 2025
概括
在人类免疫缺陷病毒 (HIV) 患者中,外周动脉疾病 (PAD) 正在增加,原因是高活性抗逆转录病毒疗法 (HAART) 的预期寿命更长. 下肢再血管化对于患有PAD的HIV患者来说是安全和有益的.
科学领域:
- 血管外科 血管外科
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 高活性抗逆转录病毒疗法 (HAART) 增加了人类免疫缺陷病毒 (HIV) 患者的寿命.
- 周围动脉疾病 (PAD) 的患病率在艾滋病毒患者中正在上升.
- HAART是加速动脉样硬化的一个独立风险因素,使PAD管理复杂化.
研究的目的:
- 审查有关PAD的HIV患者下肢再血管化的趋势和结果的文献.
主要方法:
- 进行了对全文文章的叙事审查.
- 文献搜索涵盖了从创立到2024年的时间段.
主要成果:
- 艾滋病毒患者的PAD管理得到了改进,人们更好地了解了病理生理学和干预效益.
- 患有PAD的HIV患者年轻,更容易进行开放式外科绕道或大截肢,导致更长的住院时间和更高的成本.
- 下肢再血管化是安全的,在无症状的艾滋病毒患者中具有良好的结果,病毒载量和CD4计数得到控制.
结论:
- 在接受HAART的老龄化HIV患者中,PAD是越来越令人担忧的.
- 下肢再血管化为患有PAD的HIV患者提供了显著的好处.
- 在这个队列中需要进一步研究重血管化后的长期结果.
相关概念视频
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