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2型糖尿病和MASLD患者的管理:概述和联合声明

Yasmina Chouik¹, Clémence M Canivet², Jean-Baptiste Julla³

¹Service d'Hépatologie, Hôpital de la Croix-Rousse, Institut d'Hépatologie de Lyon, Hospices Civils de Lyon; Université Claude Bernard Lyon 1, Lyon, France.

Diabetes & metabolism

|October 17, 2025

概括

2型糖尿病和与代谢功能障碍相关的脂肪性肝病经常同时存在. 在糖尿病患者中查肝纤维化对于管理并发症和指导治疗策略至关重要.

科学领域:

肝病学肝病学是一种肝病学.
内分泌学在内分泌学.
内部医学内部医学

背景情况:

2型糖尿病 (T2D) 和代谢功能障碍相关的脂肪性肝病 (MASLD) 是普遍存在的,日益增长的全球健康问题.
共享的病理生理学将T2D和MASLD联系在一起,与MASLD相关的肝纤维化增加T2D患者的肝脏和肝外并发症风险.
建议在T2D中对先进的MASLD相关纤维化进行系统查,这是由于高患病率和特定的管理需求.

研究的目的:

总结有关MASLD查和治疗T2D患者的当前知识.
为医疗保健专业人员,特别是糖尿病专家和初级保健医生提供临床路线图.
在存在显著纤维化时指导药物治疗的适应,以减缓肝病的进展和减少临床事件.

主要方法:

专家的共识和知识的总结.
专注于T2D中MASLD特有的饮食,行为和药物管理.
在T2D中对MASLD管理的减肥程序的审查.

主要成果:

MASLD和T2D有共同的病理生理路径.
与MASLD相关的纤维化是T2D并发症的关键预测因素.
查和量身定制的管理对于改善结果至关重要.

结论:

对T2D和MASLD的综合管理至关重要.
在T2D患者中早期检测肝纤维化可以进行有针对性的干预.
调整治疗策略可以减轻肝病的进展和相关风险.

关键词:

腹腔外科手术是什么意思纤维化纤维化纤维化生活方式干预措施马什 (MASH) 是一个非常重要的产品.监控监控监控监控药理治疗药理治疗

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