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Updated: Jan 14, 2026

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TDP-43和Tau之间的直接相互作用促进了它们的共同凝结,同时抑制了Tau纤维的形成和播种

Francesca Simonetti1,2,3, Weijia Zhong4, Saskia Hutten3

  • 1Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Munich, 81377, Germany.

The EMBO journal
|October 17, 2025
PubMed
概括

和TDP-43蛋白相互作用,在阿尔茨海默氏症 (AD) 中形成联合聚合物. 这种相互作用抑制了Tau病理,同时可能导致AD患者的TDP-43病理.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的疾病.阶段分离 阶段分离播种播种 播种播种在TDP-43中使用.塔乌·塔乌 (Tau Tau) 是一个

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