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黑胡知识库 (BlackPepKB):一个集中的网络资源,用于黑胡 (Piper nigrum L.) 的功能基因组

L M D Bawanga¹, D R R Wijewardene², Praveena Sarathchandra³

¹Department of Plant Sciences, Faculty of Science, University of Colombo, Colombo, Sri Lanka.

|October 17, 2025

概括

黑胡研究得到了BlackPepKB的推进,这是第一个基因组数据库,详细介绍了2,503个转录因子基因及其功能. 这种资源有助于基因研究和培育这一重要的香料作物.

科学领域:

基因组学就是基因组学.
植物科学植物科学
生物信息学是一种生物信息学.

背景情况:

黑胡 (Piper nigrum L.) 是一种重要的香料作物,具有经济和药用价值.
现有的基因组和转录基因组数据缺乏研究人员和育种者的集中资源.
黑胡的蛋白质和转录因子 (TFs) 的功能注释是不完整的.

研究的目的:

建立第一个专门用于黑胡的基因组数据库.
为功能基因组学研究和育种提供一个全面的资源.
为了注释和分析黑胡的转录因子目录.

主要方法:

2,503个转录因子基因 (PnTFs) 的识别和分类,分为62个家族.
蛋白质与蛋白质相互作用网络分析以确定枢纽TF.
基因本体学 (GO) 基于63,463种蛋白质的功能注释.
开发黑胡知识库 (BlackPepKB) 平台,并使用集成的工具.

主要成果:

确定了2,503个PNTF基因,包括471个可能参与应激反应的内在无基因.
发现了171个枢纽PNTF作为生物过程的关键调节者.
标注56.2%的黑胡蛋白质与GO条款.
推出了BlackPepKB,其中包括eFP浏览器,JBrowse2,BLAST,GeneViz,PepperExp,PepperClust和GO-Pep工具.

结论:

BlackPepKB是黑的首个基因组数据库,为功能基因组学提供了一个全面的平台.
这个资源促进了先进的遗传研究和黑胡的分子育种.
BlackPepKB是公开可访问的,支持研究社区.

关键词:

黑胡是一种黑胡.这是一个EFP浏览器.公共服务条款公共服务条款基因组数据库是基因组数据库.国家统一计划 (SNP) 是一个国家统一计划.转录因子转录因子

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