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Updated: Jan 14, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Published on: July 29, 2014

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一项系统性审查和元分析,以确定高剂量阿片类药物治疗的垂直极限

Franziska Dickmann1, Julia Stingl2, Angelika Lampert3,4

  • 1Department of Palliative Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany.

Neurological research and practice
|October 17, 2025
PubMed
概括

这项研究定义了慢性疼痛的高剂量阿片类药物治疗值. 一个元分析确定大约138毫克/天作为高剂量,癌症和非癌症疼痛的变化.

关键词:
癌症 疼痛 癌症 疼痛慢性疼痛是一种慢性疼痛.高剂量的高剂量非癌症性疼痛是没有癌症的.在阿片类药物中,阿片类药物这是一个值.

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