氧化应激触发介导的TXNIP降解和NF-κB激活,促进慢性阻塞性肺病

Pei-Yun Lin1,2, Kang-Yun Lee3,4,5,6, Shu-Chuan Ho2,5

  • 1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei , 110, Taiwan.

Respiratory research
|October 17, 2025
PubMed
概括

香烟烟雾会引发氧化应激,导致TXNIP的中介性降解. 这个过程激活NF-κB,导致巨细胞的炎症,并导致慢性阻塞性肺病 (COPD) 的发展.

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