老年患者骨折后吸烟和手术前深静脉血栓的相关性:一个倾向性得分匹配的研究
1Department of Orthopedics, Zigong First People's Hospital, Sichuan Province, No. 42, Yizhi Road, Shangyihao Street, Zigong, 643000, People's Republic of China. 13568531664@163.com.
Journal of orthopaedic surgery and research
|October 17, 2025
概括
在老年人骨折患者中,吸烟显著增加了手术前深静脉血栓形成的风险. 较高的吸烟强度与发展DVT的可能性更高相关,强调吸烟是关键风险因素.
科学领域:
- 老年医学 老年医学
- 血管外科 血管外科
- 流行病学 流行病学
背景情况:
- 部骨折在老年患者中很常见,通常需要手术.
- 深静脉血栓 (DVT) 是一个重要的术后并发症.
- 在这个人群中,吸烟对手术前DVT风险的影响需要进一步研究.
研究的目的:
- 为了检查吸烟与老年骨骨折患者手术前DVT发生率之间的关联.
- 确定吸烟是否是手术前DVT的独立风险因素.
- 探索吸烟强度和DVT风险之间的潜在剂量反应关系.
主要方法:
- 对1,190名老年关节骨折患者进行了回顾性队列研究.
- 患者被分为吸烟者和非吸烟者.
- 多变量逻辑回归和倾向得分匹配 (PSM) 来控制混者.
- 剂量反应分析以评估吸烟强度.
主要成果:
- 吸烟者在手术前发生的DVT的发生率明显高 (27.6%与PSM前的11.9%,PSM后的26.3%与11.4%).
- 吸烟是术前DVT风险增加的独立预测因子 (调整后的OR从2.75到3.68不等).
- 在吸烟强度和DVT风险之间明显存在剂量反应关系.
结论:
- 吸烟是老年人骨骨折患者手术前DVT的重要独立风险因素.
- 增加吸烟强度与手术前 DVT 的风险更高有关.
- 这些发现强调了戒烟在这个患者群体中的重要性.
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