MASLD与妇女健康之间的关系:一篇综述
Pavlina Jancova1,2, Khaled Ismail3, Lucie Vistejnova1,2
1Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Women's health (London, England)
|October 18, 2025
概括
与代谢功能障碍相关的脂肪性肝病 (MASLD) 显著影响女性.
科学领域:
- 肝病学和代谢障碍 肝病和代谢障碍
- 妇女健康 妇女健康
- 内分泌学 在内分泌学.
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为NAFLD,是一种与肥胖和代谢综合征相关的流行慢性肝病.
- MASLD可能会发展为严重的肝损伤,包括肝硬化和肝细胞癌,是肝移植的主要原因.
- MASLD不成比例地影响女性,特别是那些患有多囊性卵巢综合征 (PCOS) 和更年期期间的女性.
研究的目的:
- 审查有关MASLD的当前知识,重点关注病原,管理和差异.
- 突出MASLD对妇女一生健康的具体影响.
- 告知临床医生关于MASLD在妇女医疗保健中的相关性.
主要方法:
- 关于MASLD病原体,临床管理和流行病学数据的综合文献综述.
- 对调查性激素,PCOS,更年期和怀孕在MASLD中的作用的研究进行分析.
- 在MASLD背景下对激素替代疗法和母乳养的证据的评估.
主要成果:
- 结核复合症和更年期的患病率是MASLD患病率的两倍以上;结核复合症增加的风险/严重程度与BMI无关.
- 怀孕期间的MASLD会增加妊娠糖尿病和孕前的风险;长期母乳养可以降低后代的风险.
- 更年期激素治疗的作用是有争议的,但通过皮肤输送的雌激素与特定的孕激素可能是有益的.
结论:
- 临床医生必须认识到MASLD在妇女一生中对她们的独特影响.
- 了解荷尔蒙的影响对于管理女性MASLD至关重要.
- 管理MASLD需要量身定制的方法,考虑到女性特有的因素和生命阶段.
关键词:
马什 (MASH) 是一个非常重要的产品.马斯尔德 马斯尔德是什么意思这是NAFLD.纳什·纳什 (Nash Nash) 是一个名为纳什的城市.孕期糖尿病 孕期糖尿病激素疗法激素疗法是一种激素疗法.更年期 绝经 更年期多囊性卵巢综合征多囊性卵巢综合征怀孕 怀孕 怀孕 怀孕 怀孕蒸汽症是一种蒸汽症.脂肪性肝病肝脏疾病.更多相关视频
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