患者导向教育的有效性,以维持抑郁症:一个务实的试验
Katie Fitzgerald Jones1,2, Kelly Stolzmann3, Jolie Wormwood3,4
1New England Geriatric Research Education and Clinical Center, VA Boston Healthcare System, 150 South Huntington Ave, Jamaica Plain, MA, 02130, USA. Katie.jones4@va.gov.
Drugs & aging
|October 18, 2025
概括
患者教育材料有效地促进了对老年人潜在不合适药物 (PIM) 的处方. 这种策略是安全的,并导致持续减少药物使用,改善患者的治疗结果.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 超过三分之一的老年人使用潜在不合适的药物 (PIM).
- 多药和PIM在患有慢性疾病的老年人中更为普遍.
- 处方药在临床实践中未得到充分利用,尽管它有好处.
研究的目的:
- 评估患者参与策略的有效性,可持续性和安全性.
- 评估以患者为导向的教育对老年人减少药物服用的影响.
主要方法:
- 一个实用试验,涉及三个医疗机构.
- 患者收到有关特定PIM (PPI, gabapentin,糖尿病药物) 或通常护理的教育小册子.
- 干预后6个月和12个月评估了结果.
主要成果:
- 接受干预的患者在12个月后实现抑郁症的可能性显著增加 (OR=1.19).
- 该策略在6个月和12个月 (OR=1.32) 显著促进了持续的抑郁症.
- 没有观察到短期或延迟抑郁症的显著增加;发生了五次潜在的不良药物撤销 (0.2%).
结论:
- 低强度,以患者为导向的教育是抑郁症的有效实施策略.
- 这种方法促进并维持了老年人安全地减少药物使用.
- 患者参与可以克服临床实践中抑郁症的障碍.
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