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Updated: Jan 6, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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在RIβ中的N3A基因在PKA激活中介于cAMP和ATP之间的全交叉

Jian Wu1, Jessica G H Bruystens1, Puspashree Sahoo2

  • 1Department of Pharmacology, University of California at San Diego, San Diego, California, USA.

Protein science : a publication of the Protein Society
|October 18, 2025
PubMed
概括

依赖于cAMP的蛋白激酶 (PKA) 的RIβ子单元对大脑功能至关重要,并与疾病有关. 新的结构揭示了AKAP结合和氧化如何改变其构造,可能解释cAMP激活机制.

关键词:
这就是PKA PKA.这就是PRKAR1B.异构体结构的结构是异构体结构.整酶全酶是一种全酶.

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