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在转移性肺癌出现时绘制症状网络:与年龄相关的差异和来自集群分析的见解

Mateus Trinconi Cunha¹, Khloe Campos², Carla Rosario³

¹Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Journal of geriatric oncology

|October 18, 2025

概括

转移性肺癌患者无论年龄,症状负担都很高. 幸福感,疲劳和抑郁症等关键症状是相互关联的和中心的,指导支持性护理以改善生活质量.

科学领域:

在瘤学瘤学.
抚慰性护理是一种缓解性护理.
老年病的医生老年病的医生

背景情况:

转移性肺癌经常导致患者出现大量的症状负担.
了解基线症状对于有效的患者管理至关重要.

研究的目的:

在被诊断为转移性肺癌的成年人中描述基线症状.
为了确定症状体验的年龄相关差异.
检查症状集群及其相互关联.

主要方法:

追溯分析埃德蒙顿症状评估系统评分从359名新诊断的第四阶段肺癌患者 (2015-2016) 的追溯分析.
患者按年龄分层 (<65岁与≥65岁).
统计方法包括描述性统计,回归,主要组件和网络分析.

主要成果:

平均总症状困扰得分为22分. 出现了两个群体:身体 (疼痛,疲劳,恶心等). 和心理 (抑郁症,焦虑症).
年龄组之间没有显著的整体症状负担差异,尽管老年患者报告了更多的食欲丧失 (p=0.04).
网络分析强调了福祉,疲劳和抑郁症作为核心的,相互关联的症状.

结论:

老年和年轻的转移性肺癌患者在诊断时面临着类似的高症状负担.
对所有年龄段的人来说,全面的症状评估至关重要.
识别出症状集群和中心症状可以为提高生活质量提供有针对性的干预措施.

关键词:

年龄年龄年龄年龄年龄年龄肺癌是一种肺癌.转移性转移性症状负担是因为症状负担.症状集群是一种症状集群.

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