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冷血功能化黄素纳米配方:稳定性,持续释放,增强ADH/ALDH活动

Shuhong Li¹, Yaqing Bian¹, Wenwen Yu¹

¹College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.

|October 18, 2025

概括

冷等离子技术增强了库尔库明 (Cur) 在 zein-fucoidan纳米颗粒中的封装. 这提高了Cur的稳定性,在胃肠道中持续释放,并在消化后保持其功能活性.

科学领域:

材料科学材料科学材料科学
生物技术是生物技术.
纳米技术纳米技术

背景情况:

黄素的生物活性受到口服后稳定性和无活化不佳的阻碍.
开发有效的输送系统对于增强黄素的治疗潜力至关重要.

研究的目的:

使用冷等离子技术合成ain-fucoidan纳米颗粒,以改善黄素封装.
评估冷等离子治疗对纳米粒子特性和黄素稳定性的影响.

主要方法:

封装黄素的zein-fucoidan纳米颗粒通过冷等离子技术合成.
纳米粒子的特征包括粒子大小,表面电荷,封装效率和负载能力.
分析了齐恩,富可伊丹和黄素之间的相互作用.

主要成果:

冷血治疗 (80W,3分钟) 优化了,富可伊丹和黄素之间的结合.
CP-zein-FU NPs表现出小粒子大小 (133 nm),高表面电荷 (-37.36 mV) 和增强的稳定性.
封装效率 (86.14%) 和加载 (2.85%) 显著提高,并增强了相互作用.

结论:

冷等离子技术是有效的创建稳定的黄素/zein-fucoidan纳米粒子.
开发的纳米颗粒增强了黄素在胃肠道中的稳定性,并确保持续释放.
这种方法保留了黄素的功能活性,为口服输送提供了一个有前途的策略.

关键词:

酒精排毒效应酒精排毒效应冰冷的等离子体是什么?纳米输送系统的纳米输送系统.稳定的稳定性稳定的稳定性持续释放的持续释放

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