修订了Brachycera内部的进化关系和中双体的早期起源
Peter O Mulhair1, Alessandro Pennati2, Carlos Herrera-Ubeda3
1Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L59 7ZB, UK.
Current biology : CB
|October 18, 2025
概括
对于中前后轴形成至关重要的双基因,存在于非循环类物种中,这表明其更早的进化起源. 这种基因很可能出现在 Heterodactyla 的共同祖先中,随后多次丢失.
科学领域:
- 发展生物学 发展生物学
- 进化遗传学 进化遗传学
- 昆虫的新生学 昆虫的新生学
背景情况:
- 前后轴的规范对于胚胎发育至关重要,双基因在像Drosophila melanogaster这样的旋飞中发挥着关键作用.
- 双基因起源于祖先的Hox3基因 (昆虫中的zen),其存在和功能在昆虫物种之间有所不同.
研究的目的:
- 为了研究二动物 () 中双基因的进化史和遗传分布.
- 为了确定双基因出现的时间,并识别飞机进化过程中其损失的实例.
主要方法:
- 对186种二动物的基因组分析,以确定双基因的存在.
- 遗传学分析以重建早期Brachycera血统的进化关系.
- 在Bombylius major (黑边蜜蜂) 中确认双边形mRNA表达和局部化.
主要成果:
- 双基因在非环拉芬的中被发现,包括蜜蜂 (Bombyliidae) 和尖刀 (Therevidae).
- 在Bombylius major.中确认了双形mRNA的母体表达和前部局部化.
- 一个经过修订的二体系学说表明,双体在Heterodactyla (Bombyliidae,Asiloidea,Eremoneura) 的祖先中出现,并至少被丢失了16次.
结论:
- 双基因在类动物中具有比以前想象的更广泛的进化历史,起源于早期的Brachycera.
- 在整个的进化过程中,双基因的多个独立损失发生了.
- 这些发现增强了对早期昆虫发育,类遗传和基因演变的理解.
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