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Updated: Jan 14, 2026

In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay
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SDF2和SDF2L1是DNAJB11的必要辅助因子,用于Polycystin-1的处理

Tilman Busch1, Björn Neubauer1, Sophia Sediq1

  • 1Department of Medicine IV - Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

The Journal of biological chemistry
|October 18, 2025
PubMed
概括

DNAJB11突变通过损害Polycystin-1 (PC1) 处理导致脏疾病. 这项研究确定SDF2和SDF2L1是正常PC1处理和功能所必需的关键DNAJB11复合体成员.

关键词:
在 ADPKDD 中,在DNAJB11中使用.在GPS的分离.聚西斯-1 是一种多素.这就是SDF2的原因.这就是SDF2L1的原因.多囊性脏疾病多囊性脏疾病

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