沉思与在双相情感障碍中使用迷幻药 - - 有什么区别?
Lauren N Vale1, Maya Ibrahim2, Leonardo Fávaro-Pereira3
1Louis A. Faillace Department of Psychiatry & Behavioral Sciences, UTHealth Houston, 1941 East Rd., Houston, TX 77054, USA.
Journal of affective disorders
|October 18, 2025
概括
曾使用过迷幻药物的双相情感障碍 (BD) 患者表现出比考虑使用的患者更积极的态度和开放性. 之前的迷幻体验可能会塑造对双相情感障碍患者使用的看法和动机.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
背景情况:
- 迷幻药在心理健康治疗方面表现有前途.
- 双极性障碍 (BD) 患者经常被排除在迷幻研究之外,因为担心不良精神事件.
- 了解BD个体考虑使用迷幻药的动机和特征至关重要.
研究的目的:
- 探索以前曾使用过经典迷幻药物的双相情感障碍 (BD) 个体的动机,期望和人格特征 (实验者) 与考虑未来使用 (沉思者) 的人.
- 为了在社会人口统计学,心理和心理健康变量上比较实验者和观察者.
主要方法:
- 观察性研究比较了两个群体:曾使用过迷幻药物 (实验者) 的BD个体和考虑使用它们的人 (沉思者).
- 评估社会人口统计学,心理和心理健康变量.
- 两组之间的态度,动机,期望和个性特征的比较.
主要成果:
- 实验者和观察者在社会人口统计学或心理健康变量方面没有差异.
- 与沉思者相比,实验者对迷幻药物表现出更积极的态度和更高的"对经验的开放性".
- 实验者更强烈地支持使用迷幻药物的特定动机,而沉思者则更担心潜在的负面影响.
结论:
- 双相情感障碍患者之前的迷幻体验与更积极的感知和更强烈的使用动机有关.
- 人格特征,特别是"对经验的开放性",可能会区分那些使用过迷幻药的人和那些正在考虑使用它的人.
- 调查结果为有关BD患者使用迷幻药的讨论提供了信息,即使是在临床试验背景下,也突出了风险益处评估和患者咨询的领域.
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