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相关概念视频

Gut-Brain Axis01:22

Gut-Brain Axis

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The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such...
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相关实验视频

Updated: May 2, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

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微生物肠型,大脑结构和工作记忆之间的关联:一个结合结构和扩散MRI研究.

Zhonghao Rao1, Yu Shi1, Min She1

  • 1Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Research Center of Clinical Medical Imaging, Anhui Province, Hefei 230032, China; Anhui Provincial Key Laboratory for Brain Bank Construction and Resource Utilization, Hefei 230032, China.

NeuroImage
|October 18, 2025
PubMed
概括

肠道微生物体的肠型与大脑结构的差异有关,特别是在前额叶皮层. 这个大脑区域调解了肠型和工作记忆性能之间的关系.

关键词:
大脑结构 大脑结构输入型 输入型 输入型我们的肠道微生物组.这就是为什么MRI是MRI.工作记忆 工作记忆

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
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Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
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相关实验视频

Last Updated: May 2, 2026

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12:21

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25.7K
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科学领域:

  • 微生物组研究的研究.
  • 神经成像是一种神经成像.
  • 认知神经科学是一种认知神经科学.

背景情况:

  • 肠型分析根据肠道微生物组成对个体进行分类.
  • 肠肠类型影响大脑功能和工作记忆,但大脑的结构联系尚不清楚.

研究的目的:

  • 调查肠道肠类型和大脑结构之间的关系.
  • 检查大脑结构如何调解肠型和工作记忆之间的联系.

主要方法:

  • 从511名健康成年人收集了便样本,用于16S rDNA amplicon测序,以确定肠型 (Bacteroides,Prevotella,Ruminococcaceae).
  • 使用结构和扩散MRI来评估大脑灰质形态和白质完整性.
  • 分析了大脑结构中的肠型间差异及其与工作记忆的相关性.

主要成果:

  • 在肠型之间观察到前额叶皮层皮层厚度和白质通道 (大脑脚,环) 的显著差异.
  • 前额叶皮层厚度与工作记忆性能相关.
  • 前额叶皮层的厚度显著介导了肠型和工作记忆之间的关联.

结论:

  • 肠道微生物群的肠型与独特的大脑结构特征有关.
  • 前额叶皮层结构在肠道微生物群-大脑-认知轴中起着调解作用.
  • 这些发现支持进一步研究微生物群与大脑认知关系.