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慢凝血连续波环光凝血与微脉冲激光治疗过程在耐火性玻璃眼:一个随机临床试验

Luiz A F Beniz¹, Mariana C Ikeda¹, Eloisa G R M Teixeira²

¹Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.

Ophthalmology. Glaucoma

|October 18, 2025

概括

慢凝血连续波循环光凝血 (SC-CPC) 在治疗耐火性玻璃眼症方面显著优于微脉冲激光治疗 (MP-LT),在18个月内实现更好的眼内压力控制和更低的失败率.

科学领域:

眼科医生眼科眼科
视光眼管理视光眼管理
激光疗法是一种激光疗法.

背景情况:

耐火性玻璃眼症在眼内压力 (IOP) 管理方面是一个重大挑战.
透膜二极管激光循环光凝是一种治疗晚期玻璃眼的治疗选择.
对比不同的激光模式对于优化治疗结果至关重要.

研究的目的:

为了比较慢凝血连续波环光凝血 (SC-CPC) 与微脉冲激光治疗 (MP-LT) 的疗效.
为了评估经过透膜二极管激光环光凝固的耐火性玻璃眼患者的结果.
评估18个月的治疗成功,内压降低和并发症率.

主要方法:

一个前性的,双中心随机临床试验,涉及60个眼睛的60名患有医学无法控制的玻璃眼病的患者.
患者随机分配到SC-CPC或MP-LT,使用标准化的激光参数.
成功的定义是术后内血压在6-18mmHg之间,≥20%的降低,没有进一步的干预或显著的视力损失.

主要成果:

与MP-LT (30.0%) (P = 0.001) 相比,SC-CPC的治疗成功率显著更高 (70.0%).
在SC-CPC组呈现较低的平均内血压 (18.4 mmHg vs. 22.5 mmHg,P = 0.005) 和更大的内血压减少 (23.1% vs. 11.5%,P = 0.020).
在SC-CPC组中需要更少的内压降压药物,MP-LT组更频繁地进行重新治疗/手术.

结论:

慢凝血连续波环光凝血 (SC-CPC) 证明在控制耐火性玻璃眼的IOP方面具有卓越的疗效.
与微脉冲激光治疗 (MP-LT) 相比,SC-CPC的手术失败率较低.
这些发现支持SC-CPC作为耐火性玻璃眼患者更有效的治疗选择.

关键词:

临床试验临床试验是指临床试验的临床试验.循环摄影凝血是一种循环摄影凝血.眼光障碍症是什么眼光障碍症是什么微脉冲器是一种微脉冲.缓慢凝固的凝血是一种缓慢的凝血.

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