临床特征,微生物流行病学,以及乳腺癌相关的淋巴发中细胞炎的复发风险
Benjamin D Wagner1, Jonathan Rubin1, I-Hsin Lin2
1Department of Surgery, Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Annals of surgical oncology
|October 19, 2025
概括
蜂炎是乳腺癌相关淋巴 (BCRL) 的常见并发症,复发率很高. 放射治疗,淋巴结解剖和早期发病增加了复发风险,需要积极的预防策略.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 淋巴 edem 管理 淋巴 edem 管理
背景情况:
- 蜂炎是乳腺癌相关淋巴 (BCRL) 的常见和令人衰弱的并发症.
- 在BCRL中淋巴功能受损有助于细胞炎的发展和淋巴的进展.
- 与BCRL相关的细胞炎的临床和微生物特征需要进一步定义.
研究的目的:
- 调查BCRL患者细胞炎的患病率,临床特征和治疗结果.
- 在这个人群中确定与复发性纤维炎相关的危险因素.
- 为基于证据的BCRL相关细胞炎的治疗和预防策略提供信息.
主要方法:
- 在231名BCRL患者 (2000-2024) 中,对418例细胞炎发作进行了回顾性审查.
- 对人口,临床,微生物学和治疗数据的分析.
- 考克斯比例危险模型用于识别复发性细胞炎的危险因素.
主要成果:
- 毛皮炎的流行率为7.9% (231/2920),复发率为39.0% (90/231).
- 在阳性血液培养 (24.2%) 中,Streptococcus agalactiae是最常见的病原体.
- 复发的独立风险因素包括放射治疗 (HR 2.15),下淋巴结解剖 (HR 1.96) 和从BCRL诊断到初始细胞炎的时间缩短 (HR 0.99).
结论:
- 细胞炎代表了BCRL的严重并发症,其复发率很高.
- 放射治疗,状淋巴结解剖和早期细胞炎发作是复发的关键预测因素.
- 积极的监测和风险分层预防对于管理BCRL相关的细胞质炎和改善患者的治疗结果至关重要.
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