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Updated: Jan 14, 2026

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罗斯科维丁通过抑制CDK5-介导的Tau高酸化来缓解类似PTSD的认知障碍

Baowen Dong1, Mengmeng Chang1, Kailu Li2

  • 1College of Life Science, Northwest University, Xi'an 710069, China; Medical Innovation Center, Fourth Military Medical University, Xi'an 710032, China.

Brain research bulletin
|October 19, 2025
PubMed
概括

创伤后应激障碍 (PTSD) 涉及海马体损伤. 早期用Roscovitine向CDK5,可以减少Tau酸化,保护神经元,并减轻PTSD行为.

关键词:
循环素依赖性激酶5 5 的作用.神经新生是神经发生的过程.创伤后应激障碍 创伤后应激障碍罗斯科维他因 (Roscovitine) 是一种药物.突触性可塑性 突触性可塑性的酸化是的酸化.

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