血管追踪器2:开源软件和硬件用于追踪血管直径和评估血管功能
Matthew D Lee1, Christopher Osborne2,3, Ross Stevenson1
1Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
The Journal of physiology
|October 19, 2025
概括
血管追踪器2提供开源软件和低成本硬件,用于精确测量血管直径,从而提高血管生理学研究的可访问性. 这个平台支持多样化的成像和神经图像应用程序,使全球研究人员受益.
科学领域:
- 血管生物学和生理学
- 生物医学工程 生物医学工程
- 开源科学工具 开源科学工具
背景情况:
- 商用血管成像系统通常价格过高,限制了对先进研究工具的访问.
- 需要可访问,具有成本效益的平台来详细测量血管直径和血管功能分析.
- 现有的工具可能缺乏处理血管研究中的各种成像模式和实验条件的多功能性.
研究的目的:
- 推出VasoTracker 2,一个集成的开源平台,用于测量血管直径和血管生理学研究.
- 为研究人员提供负担得起的替代品昂贵的商业系统研究血管反应和内皮功能.
- 为了在各种成像技术中实现多点直径跟踪,并促进标准化的压力肌肉学实验.
主要方法:
- 开发自动化的多点直径跟踪软件,使用先进的边缘检测算法.
- 集成软件,支持亮场显微镜,光成像和超声记录.
- 模块化,低成本的开源压力神经镜硬件的设计,包括一个兼焦器容器室和VasoMoto可编程压力控制器.
主要成果:
- 血管追踪器2软件能够通过多种成像方式对分支血管进行精确的直径分析.
- 自动化压力协议促进了标准化的肌源性音调实验,实时和离线数据分析.
- 瓦索摩托压力控制器和容器室允许以大大降低成本建造一个功能性的压力肌肉学系统.
结论:
- 血管追踪器2通过提供免费的开源软件和低成本硬件来民主化先进的血管研究.
- 该平台的灵活性和成本效益提高了全球研究血管动态的研究人员的可访问性.
- 开源性质鼓励修改和扩展,促进血管生理学研究的创新.
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