狗胃粘膜肉瘤:一种新的瘤类型
S F Lane1, Rja Hughes2, A A Ciavarella2
1Greencross Veterinary Hospital, Werribee, Victoria, Australia.
Australian veterinary journal
|October 19, 2025
概括
这份病例报告详细介绍了第一例狗胃粘膜肉瘤,这是一种罕见的瘤,与肌肉层肉瘤不同. 尽管手术切除和化疗,狗经历了复发和转移,包括胰腺.
科学领域:
- 兽医瘤学 兽医瘤学
- 比较病理学比较病理学
背景情况:
- 胃瘤在狗中很罕见,占所有瘤的不到1%.
- 中介细胞瘤通常来自胃肌层,占狗胃瘤的10-30%.
- 从肌肉层开始的胃肉瘤以前没有被记录.
研究的目的:
- 报告狗胃粘膜肉瘤的第一个病例.
- 为了将这种瘤与在肌肉层中产生的初级胃肠道瘤区分开来.
- 描述这种罕见的狗胃瘤的临床表现,治疗和结果.
主要方法:
- 调查了一名7岁的雌性消毒拉布拉多犬,患有慢性吐和贫血.
- 腹部成像显示出一个大型的,形的胆道质量.
- 进行了手术切除 (Billroth I),随后为局部复发进行了第二次手术 (Billroth II),辅助化疗和息治疗.
主要成果:
- 组织病理学证实了慢性高性胆道胃,与非典型的螺旋细胞扩散局限于粘膜.
- 在Billroth I治疗后5.5个月发生了局部复发,随后发生了omental转移.
- 鉴定了胰腺转移和局部瘤复发,在最初的症状出现20个月后导致安乐死.
结论:
- 这是首个报告的狗胃粘膜肉瘤病例,与基于肌肉的肉瘤不同.
- 脚质量最初是可切除的,但观察到局部复发和远程转移,包括胰腺.
- 胰腺转移代表了对狗胃肠道肉瘤的新发现.
更多相关视频
04:25Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
11.2K
07:47Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
Published on: September 15, 2023
2.1K
相关概念视频
Intestinal Obstruction I: Introduction
Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology
Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
