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Updated: Jan 14, 2026

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基于实用性的剂量优化方法用于多剂量随机试验设计,考虑多个终点

Gina D'Angelo1, Guannan Chen1,2, Di Ran1

  • 1Oncology Biometrics, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.

Pharmaceutical statistics
|October 20, 2025
PubMed
概括

新的方法U-MET-m和CUI-MET通过优化剂量选择来增强瘤学临床试验. 这些方法有效地使用多个终点和剂量确定最佳生物剂量 (OBD).

关键词:
这就是CUI-MET.在U-MET-m.剂量优化剂量优化剂量随机化剂量随机化最优的生物剂量.公用事业公用事业公司

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