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在患有全身性红斑狼的患者中,使用光学一致性断层扫描血管图的状血管区区域

Ploysai Rujkorakarn¹, Kanyanat Pholprathom², Parinya Srihatrai²

¹Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, 90110, Thailand.

Clinical ophthalmology (Auckland, N.Z.)

|October 20, 2025

概括

与对照组相比,全身性红斑狼 (SLE) 患者没有显示出更大的状血管区域. 中央视网膜厚度在SLE患者中较薄,没有发现显著的药物相关性.

科学领域:

眼科医生眼科眼科
类风湿病学类风湿病学
医疗成像医学成像

背景情况:

系统性红斑狼 (SLE) 可以影响包括眼睛在内的各种器官.
在SLE患者的眼部表现需要仔细监测.
光学连贯断层扫描血管学 (OCT-A) 允许详细可视化视网膜血管结构.

研究的目的:

在SLE患者中使用OCT-A.A.来评估表面状血管区域 (SFAZ) 和深状血管区域 (DFAZ).
为了确定SFAZ和DFAZ区域是否与SLE治疗中使用的特定药物有关.
为了比较SLE患者和健康对照人群之间的状血管区域尺寸.

主要方法:

进行了一项横截面的观察性研究.
分析了36名SLE患者的36只眼睛和33名健康对照者的33只眼睛.
Spectralis OCT-A用于测量SFAZ,DFAZ和中枢视网膜厚度 (CRT).

主要成果:

在SLE患者和健康对照者之间没有观察到SFAZ和DFAZ区域的显著差异.
与对照组相比,SLE患者的中枢视网膜厚度 (CRT) 显著较薄.
SFAZ和DFAZ地区与氧化/的持续时间或免疫抑制治疗没有显著的关联.

结论:

与健康个体相比,SLE患者的状血管区域尺寸没有显著改变.
减少中枢视网膜厚度是SLE患者的一个值得注意的发现.
目前的SLE药物没有与SFAZ或DFAZ显著相关.

关键词:

足骨非血管区 (FOVAL AVASCULAR ZONE) 是指足骨非血管区 (FOVAL AVASCULAR ZONE) 的一个区域.光学连贯性断层扫描血管图谱系统性红血性狼 (Systemic Lupus Erythematosus) 是一种全身性狼.

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