具有神经精神病学恶化和体重减轻的类固醇耐药性皮疹:现代皮草病例
Harshita Ryali1, Hagar Elgezeri2, Humaira Ahmed3
1Dermatology, North Bristol NHS Trust, Bristol, GBR.
Cureus
|October 20, 2025
概括
色素是一种尼亚缺乏症,可以引起皮肤炎,腹和痴呆症. 这一案例凸显了在患有无法解释的神经精神和皮肤症状的患者中考虑佩拉格拉的重要性,即使有现代医疗护理.
科学领域:
- 营养 营养 营养 营养 营养
- 皮肤病学 皮肤病学
- 神经学 神经学
背景情况:
- 佩拉格拉是一种多系统性疾病,由素 (维生素B3) 缺乏引起.
- 虽然由于食品强化不那么常见,但皮拉格拉仍在脆弱人群中发生.
- 典型的症状包括皮肤炎,腹和痴呆症.
研究的目的:
- 报告一个模仿皮肤肌炎的贝拉格拉病例,该病例发生在限制性饮食的患者身上.
- 强调在复杂的神经精神和皮肤病的差异诊断中考虑贝拉格拉的重要性.
- 突出营养疗法的疗效在治疗贝.
主要方法:
- 一个50岁女性的案例研究,她有精神和神经问题的历史.
- 临床表现包括皮疹,消化不良,腹和认知能力下降,最初被治疗为皮肤肌炎.
- 诊断是在确定长期限制性性饮食后确立的,随后是尼古丁胺和B族维生素补充剂的治疗.
主要成果:
- 患者的症状,包括皮疹,消化不良,腹和神经认知能力下降,对皮质类固醇无反应.
- 在被诊断为佩拉格拉并开始服用维生素B3补充剂后,出现了快速和持续的症状消失.
- 这证明了营养干预在控制小的有效性.
结论:
- 无论地理位置或营养状况如何,在出现神经精神病和皮肤病症状组合的患者中,应考虑佩拉格拉.
- 早期诊断和营养疗法治疗至关重要,因为未经治疗的小可能是致命的.
- 限制性饮食,如性饮食,可能会增加素缺乏症和随后的皮风险.
更多相关视频
10:27Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
25.0K
08:33Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
Published on: June 25, 2019
8.6K
相关概念视频
Anorexia Nervosa
957
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
957
Chronic Kidney Disease II: Clinical Manifestations
547
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
547
Skin Diseases and Disorders
5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
635
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
635
Nephrotic Syndrome I : Introduction
493
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
493
Bulimia Nervosa
666
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
666
