通过胸腔镜肺部活检诊断出两个肺部化颗粒瘤病例
Madoka Goto1, Yasuhisa Ichikawa1, Hideki Tsubouchi1
1Thoracic Surgery, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, JPN.
Cureus
|October 20, 2025
概括
肺化颗粒瘤是一种罕见的肺瘤,存在诊断方面的挑战. 确定的诊断需要永久的组织学样本,因为冷部位分析可能会产生误导性.
科学领域:
- 肺部病理学 肺部病理学
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 肺化颗粒瘤 (PHG) 是一种罕见的良性肺瘤.
- 在胸部CT扫描中,PHG通常呈现为双边多重肺结节.
- 在手术前和手术期间诊断PHG是具有挑战性的.
研究的目的:
- 报告两例肺部化颗粒瘤的病例.
- 突出PHG的诊断困难,特别是在手术内冷部位分析中.
- 强调PHG诊断的终极遗传病理学检查的重要性.
主要方法:
- 两例老年女性在CT扫描上有偶发的双边肺结节.
- 视频辅助胸腔镜肺活检用于诊断.
- 在手术期间进行冷部位分析,然后对手术样本进行体病学检查.
主要成果:
- 在手术期间的冷部位分析表明,在这两种情况下都有纤维化.
- 组织病理学检查证实了肺部化颗粒瘤,其特征是密集的化原和炎症透.
- 在随访期间 (12个月和11个月) 没有观察到结节的进展.
结论:
- 肺部化颗粒瘤的诊断在手术前和手术期间是困难的.
- 冷部位分析可能会误导,暗示良性纤维化.
- 来自肺活检的永久组织学样本对于PHG的准确诊断至关重要.
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