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Updated: Jan 14, 2026

TRUE Gene Silencing: Screening of a Heptamer-type Small Guide RNA Library for Potential Cancer Therapeutic Agents
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在瘤中进行基因表达沉默疗法,专注于胃肠道和泌尿生殖道瘤

Nathan El-Ghazzi1, Antoine Italiano2, Eurydice Angeli3,4

  • 1Early Phase Trials Department, Institut Bergonié, Bordeaux, France.

Frontiers in immunology
|October 20, 2025
PubMed
概括

像反感性寡核酸 (ASOs) 和小干扰RNA (siRNAs) 这样的寡核酸疗法为癌症治疗提供了精确的基因沉默. 输送系统的进步正在提高它们的稳定性和有效性,以对抗难以治疗的癌症.

关键词:
这是一种反意义的寡核酸.这是胃肠道癌症.基因沉默疗法是一种基因沉默疗法.尿生殖系统癌症是什么这是一个小RNARNA.siRNA 是一个RNA.

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