在腹腔镜手术后老年患者手术前的跨直流刺激对术后痴呆的作用
Xi Yang1, Yu-Fei Wei1,2, Chen-Hui Ye1,2
1Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
World journal of psychiatry
|October 20, 2025
概括
在手术前的跨直流刺激 (tDCS) 显著降低了老年手术患者的术后狂妄症. 这种非侵入性脑刺激也降低了腹腔镜手术后的焦虑和抑郁.
科学领域:
- 神经科学是一个神经科学.
- 老年人手术是一门老年人手术.
- 神经调节是一种神经调节.
背景情况:
- 手术后痴呆症 (POD) 是老年手术患者常见的并发症,导致认知障碍.
- 跨直流刺激 (tDCS) 是一种非侵入性技术,可以调节大脑活动和认知功能.
- 接受大型腹腔镜手术的老年患者由于麻醉和大脑血流减少而面临POD的高风险.
研究的目的:
- 为了评估术前tDCS在降低POD发病率的疗效,在接受大腹腔镜手术的老年患者.
- 评估tDCS对术后焦虑和抑郁水平的影响.
主要方法:
- 一项随机对照试验,涉及201名接受大型腹腔镜手术的老年患者.
- 患者在麻醉前30分钟接受了积极的tDCS或假的tDCS.
- 主要终点是手术后3天内POD的发生率.
主要成果:
- 活体tDCS组 (7.0%) 的POD发病率明显低于假型tDCS组 (22.8%).
- 术后焦虑和抑郁的得分在术后第一天在tDCS组显著降低.
- 两组之间没有观察到疼痛评分的显著差异.
结论:
- 手术前的tDCS是有效的减少POD发病率在老年患者进行大腹腔镜手术.
- 一次tDCS会话也可以缓解手术后的焦虑和抑郁.
- tDCS代表了一种有前途的非侵入性策略,用于手术后管理认知和情绪并发症.
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