胃癌患者早期口服养的营养轨迹
Nan Yao1, Haixia Chen2, Leyao Han1
1School of Nursing, Lanzhou University, Lanzhou, Gansu, China.
Frontiers in nutrition
|October 20, 2025
概括
在中国的胃癌患者中,手术后的营养状况有很大差异. 像跌倒风险和癌症阶段等因素会影响这些营养轨迹,需要个性化干预.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 老年病的医生 老年病的医生
背景情况:
- 关于中国胃癌 (GC) 患者手术后营养动态的证据有限.
- 早期口服养 (EOF) 是这些患者的管理策略.
研究的目的:
- 为了确定经过EOF的GC患者的预后营养指数 (PNI) 轨迹模式.
- 确定影响这些PNI轨迹的因素.
主要方法:
- 在全胃切除术 (2019-2024) 后对124名GC患者进行了回顾性分析.
- 基于组的轨迹建模 (GBTM) 来识别PNI轨迹.
- 多项式逻辑回归用于分析相关因素.
主要成果:
- 确定了三个不同的PNI轨迹:"高营养状况" (41.9%),"快速下降" (7.3%) 和"下降-恢复" (50.8%).
- 与"高营养状况"组相比",衰退-恢复"组的基线PNI较低.
- 高莫尔斯倒数量得分,低日常生活活动 (ADL),先进的AJCC癌症阶段和血管/神经入侵与不利的轨迹有关.
结论:
- 经过EOF管理的GC患者的术后营养轨迹表现出显著的变化.
- 功能障碍 (低ADL,高MFS) 和先进的病理特征是不利的营养结果的关键决定因素.
- 针对性监测和个性化的营养干预措施对于高风险的GC患者小组至关重要.
相关概念视频
Enteral Nutrition I: Orogastric and Nasogastric Feeding
1.2K
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
1.2K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
814
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
814
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
635
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
635
Gastric Emptying
3.3K
Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
3.3K
Gastric Phase of Digestion
3.0K
The gastric phase of digestion begins as soon as food enters the stomach. The incoming food bolus triggers neural and hormonal mechanisms, which last approximately 3 to 4 hours. During this phase, the stomach undergoes significant changes to prepare the food for further digestion and absorption.
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
3.0K
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
352
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
352

