在皮肤上,启用微镜头的摄像头模块用于光斑对比光学光谱/断层扫描.
Andres Quiroga1, Lorenzo Cortese1, Manish Verma1
1ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain.
Biomedical optics express
|October 20, 2025
概括
我们开发了一个紧的斑点对比光学光谱/断层扫描 (SCOS/SCOT) 系统,使用微型镜头直接与皮肤接触. 这个系统准确地跟踪肌肉血液流动和脉动动态,为可穿戴的SCOS/SCOT设备铺平了道路.
科学领域:
- 生物医学光学 生物医学光学
- 医疗成像医学成像
- 光学光谱学是指光学光谱学.
背景情况:
- 斑点对比光学光谱/断层扫描 (SCOS/SCOT) 对非侵入性血流监测非常有价值.
- 现有的SCOS/SCOT系统通常需要光纤合,这限制了便携性和易用性.
- 开发紧,可穿戴的SCOS/SCOT设备对于持续的生理监测至关重要.
研究的目的:
- 为了引入和验证一个新的,紧的SCOS/SCOT系统,使用集成的微镜头阵列.
- 评估系统对直接皮肤接触测量和同时多距离采集的性能.
- 为了证明系统在体内监测肌肉血流和脉动动态的能力.
主要方法:
- 设计了一种集成成像SCOS/SCOT配置,在CMOS摄像头上设有113个微镜头,从而消除了光纤合.
- 该系统在使用幻象和在人前臂肌肉上进行了活体验证.
- 测量是在多个源探测器分离点和相机曝光时间进行的.
主要成果:
- 该系统与对应-扩散模型在ex vivo和in vivo测量方面表现出极好的一致性.
- 在体内数据显示高信号与噪声比率跟踪脉动性血流 (检测>4心脏波).
- 该系统对肌肉血流的微小变化表现出敏感性.
结论:
- 基于微镜头阵列的SCOS/SCOT系统可以直接与皮肤接触,同时进行多距离测量.
- 这种紧的设计克服了可穿戴SCOS/SCOT设备开发的关键挑战.
- 经过验证的系统显示了先进,非侵入性肌肉血流监测的前景.
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