复发性转移性细胞癌表现为皮肤小血管血管炎:一个病例报告
Siddanagouda B Patil1, Santosh R Patil1, Vinay S Kundargi1
1Department of Urology, Shri BM Patil Medical College and Hospital, Bangarammma Sajjan Campus, Solapur Road, Vijayapura, India.
Journal of kidney cancer and VHL
|October 20, 2025
概括
皮肤小血管血管炎 (CSVV) 很少表明复发性细胞癌 (RCC). 这一案例突显了用sunitinib成功治疗瘤性CSVV,改善皮肤病变和瘤回归.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
背景情况:
- 皮肤小血管血管炎 (CSVV) 是一种影响皮肤小血管的免疫媒介疾病.
- CSVV通常与自身免疫性疾病,感染或恶性瘤有关.
- 细胞癌 (RCC) 很少会与CSVV一起表现为副瘤综合征.
研究的目的:
- 报告一种罕见的CSVV病例,作为复发性透明细胞RCC的副瘤表现.
- 突出这一关联的诊断和治疗含义.
主要方法:
- 一位68岁的妇女有RCC病史,出现侧侧疼痛和紫色皮肤病变.
- 诊断工作包括成像,皮肤活检和免疫组织化学.
- 治疗包括sunitinib,瘤解和IVC重建.
主要成果:
- 皮肤活检证实了白细胞结合性血管炎,并有对瘤原生的免疫组织化学证据.
- 图像检测显示了复发的转移性RCC与IVC参与.
- 苏尼提尼布治疗导致皮肤病变和瘤回归的改善,随后进行了手术干预.
结论:
- 在出现新的或非典型的皮肤病变的RCC患者中,应考虑对瘤性血管炎.
- 早期诊断和向治疗,包括sunitinib,可以改善患者的治疗结果.
- 这个案例提供了对RCC的系统影响和对其瘤表现的管理的见解.
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