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A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
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局部耳道内利多卡因对耳的影响:一项随机双盲,安慰剂控制的随机研究

Tatiane Vacaro Campos1, Ricardo Ferreira Bento1, Jeanne Oticica1

  • 1Department of Ophthalmology and Otorhinolaryngology, Faculty of Medicine, Hospital das Clínicas da Universidade de São Paulo, São Paulo, SP, Brazil.

International archives of otorhinolaryngology
|October 20, 2025
PubMed
概括

与安慰剂相比,局部利多卡因耳滴没有显著减少耳. 需要进一步的研究来了解安慰剂效应和潜在的药物干扰在耳治疗.

关键词:
临床试验临床试验临床试验临床试验临床试验外部的声学装置.利多卡因 (Lidocaine) 是一种药物.局部麻醉剂 局部麻醉剂耳声 (tinnitus) 是一种耳声.局部管理局部管理.

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Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
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Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...