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含有微质的神经器官作为长期培养的大脑微生理系统

Alex Rittenhouse1, Caroline Krall1,2, Jesse Plotkin1

  • 1Center for Alternatives to Animal Testing, Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.

Frontiers in cellular neuroscience
|October 20, 2025
PubMed
概括

研究人员开发了一种新的微质集成大脑器官模型 (μbMPS),用于研究神经发育和神经炎症. 这种可扩展的模型成功地结合了微质细胞,增强了神经元活动和研究应用的成熟度.

关键词:
来自iPSC的3D模型微质细胞中的微质细胞微生理系统 (MPS) 是指微生理系统.神经器官有机物 神经器官有机物新方法方法论 (NAMs)

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