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Updated: Jan 14, 2026

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工程微生物传感器:为疾病检测提供了一个新的范式

Xuan-Ren Shi1, Yi-Fan Zhang1, Ying Zhou1

  • 1Laboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China. zpzou@ecust.edu.cn.

Journal of materials chemistry. B
|October 20, 2025
PubMed
概括

工程微生物传感器 (EMS) 提供具有成本效益,适应性和现场疾病诊断. 合成生物学方面的进步提高了体内应用的EMS可靠性和安全性,为未来的医疗用途铺平了道路.

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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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