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Updated: Jan 14, 2026

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蛋白酶激活受体1介导的矩阵金属蛋白酶在感觉神经元中的信号传递

Katie J Williams1, Giulia Galimberti1,2, James P Higham1

  • 1Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.

American journal of physiology. Cell physiology
|October 20, 2025
PubMed
概括

矩阵金属蛋白酶 (MMPs),在炎症性肠病 (IBD) 中升高,刺激感官神经元. 特定的MMP激活 nociceptive神经元上的蛋白酶激活受体1 (PAR1),可能导致IBD的疼痛.

关键词:
这是一种炎症炎症炎症炎症.炎症性肠病是一种炎症性肠病.矩阵金属蛋白酶是一种基质蛋白酶.没有感觉,没有感觉.蛋白酶激活受体的受体

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