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Brd4的损失通过Slc9b2抑制在骨质结晶发生过程中减轻了病态骨损失

Xiaohe Wang1,2, Fangji Luo1, Guiqiang Miao3

  • 1Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University & Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, Guangdong, China.

Clinical and translational medicine
|October 20, 2025
PubMed
概括

骨质疏松症中马蛋白4 (Brd4) 的含量升高,通过促进骨质细胞分化和新陈代谢,导致骨质损失. 抑制Brd4会增加骨质量,并防止病理性骨损失,提供了一个新的治疗点.

关键词:
Brd4 的意思是 Brd4在Slc9b2中,我们可以看到Slc9b2.骨质细胞生成 (osteoclastogenesis) 是一个过程.骨质疏松症是一种骨质疏松症.

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