在ADHD药物治疗期间的精神病症状:临床考虑和研究需求
Samuele Cortese1, Miguel Garcia-Argibay2, Dominic Oliver3
1Developmental "Evidence, Prediction, Implementation" (EPI) Lab, Centre for Innovation in Mental Health, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, NY, USA; Department of Precision and Regenerative Medicine-Jonic Area, University of Bari "Aldo Moro", Bari, Italy.
患有多动症的人有更高的精神疾病的风险,独立于药物治疗. 目前的证据并没有将甲基酸盐等ADHD药物与引起精神病联系起来,但建议谨慎管理.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 注意缺陷/多动障碍 (ADHD) 与精神病障碍的风险增加有关.
- ADHD药物治疗在精神病发展中的潜在作用需要仔细检查.
研究的目的:
- 为预防和管理ADHD药物治疗期间的精神病症状提供基于证据的框架.
- 引导临床医生平衡治疗效益与潜在风险.
主要方法:
- 审查关于ADHD,精神病和药物影响的现有证据.
- 探索个体对精神病的脆弱性因素.
- 发展查和管理策略.
主要成果:
- 患有多动症的个体有明显更高的精神疾病发生率,独立于药物治疗.
- 目前的证据不支持ADHD药物 (例如甲基) 和精神病之间的因果关系.
- 提出了风险评估,查和临床管理的策略.
结论:
- 积极主动,以证据为基础的方法对于在接受药物治疗的ADHD患者中管理精神病风险至关重要.
- 需要进一步的研究来完善理解和管理策略.
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