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Updated: Jul 13, 2026

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics
07:48

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics

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工程增强信号:一种高通量计算管道,用于优化CHO细胞中治疗性蛋白质的生产

Ji-Hong Zhang1, Chong Wang2, Zhao-Yang Wu3

  • 1School of Basic Medical Sciences, Henan Medical University, Xinxiang, Henan 453003, China; School of Measurement and Communication Engineering, Harbin University of Science and Technology, Harbin, Heilongjiang 150080, China; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang, Henan 453003, China.

New biotechnology
|October 20, 2025
PubMed
概括

我们开发了一个计算管道,以发现高性能信号 (SPs) 用于在中国子卵巢 (CHO) 细胞中治疗性蛋白质分泌. 这种方法显著提高了人血清白蛋白 (HSA) 的产量,优化了蛋白质的生产.

关键词:
在CHO细胞中.高通量选的高通量选人类血清专素的人类血清专素重组蛋白质生产的重组蛋白质生产信号的信号.

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