KIAA0319 在皮层神经元成熟和突触发育中发挥关键作用,通过与阅读障碍相关的基因网络

Michael J Scandura1, Mu Seog Choe1, Ferdi Ridvan Kiral1

  • 1Department of Genetics, Yale Stem Cell Center, Interdepartmental Neuroscience Program, Wu Tsai Institute, Yale School of Medicine, New Haven, Connecticut.

Biological psychiatry
|October 20, 2025
PubMed
概括

与阅读障碍相关的KIAA0319基因对神经发育至关重要. 在人类皮质器官中缺少它会破坏大脑细胞的形成和组织,这表明它在阅读之外的大脑发育中发挥了更广泛的作用.