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Updated: Jan 14, 2026

Mapping RNA-RNA Interactions Globally Using Biotinylated Psoralen
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增强的杂交-近距离标签发现了单个RNA分子的蛋白质相互作用体

Karen Yap1, Tek Hong Chung1, Erin C Hedges2,3

  • 1Centre for Developmental Neurobiology, King's College London, London, UK.

Nature communications
|October 20, 2025
PubMed
概括

一种名为HyPro的新方法绘制了细胞中的RNA-蛋白相互作用. 它确定了与肌缩性侧面硬化症 (ALS) 患者细胞中与RNA相互作用的与疾病相关的蛋白质,揭示了早期缺陷.

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