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作为SLE相关血管痴呆症的第一个表现,冷漠和认知衰退:一个病例报告

Syed Ali Bokhari¹, Dania Al-Ayyat², Anood Shukry²

¹Al Amal Psychiatric Hospital, Emirates Health Services, Dubai, United Arab Emirates. sab_191@live.com.

Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater

|October 20, 2025

概括

漠不关心可能是血管痴呆症的早期迹象,经常被误认为是抑郁症. 这一案例表明,识别诸如狼之类的自身免疫性疾病对于诊断和治疗年轻人认知衰退至关重要.

科学领域:

神经科学是一个神经科学.
血管神经学血管神经学
自免疫性疾病自免疫性疾病

背景情况:

漠不关心是痴呆症中常见但未被确诊的神经精神病症状,经常被误认为是抑郁症.
皮层下缺血性血管痴呆症带来了诊断挑战,特别是当冷漠是主要症状时.
带有抗脂标记的系统性红斑狼 (SLE) 可以表现为神经复杂症,包括血管病理.

研究的目的:

描述一个具有挑战性的皮层下缺血性血管痴呆症病例,在年轻人中以冷漠为主导症状.
强调在痴呆症综合征中区分冷漠和抑郁症的重要性.
强调自身免疫性血管病变在无法解释的血管病变和认知障碍中的作用.

主要方法:

进行了详细的神经心理评估和神经成像 (MRI).
进行了自身免疫检查,包括抗脂抗体测试.
在18个月内记录了临床过程,管理策略和患者反应.

主要成果:

神经成像显示了广泛的小血管疾病,缺口性心脏病发作和结症,与血管痴呆症一致.
自身免疫查证实了SLE与抗脂标记物,解释了血管病理.
通过心理社会干预和谨慎的药物管理,患者的情感反应有所改善.

结论:

漠不关心可能是血管痴呆的主要表现,原因是前皮下皮质电路受损.
区分冷漠和抑郁症需要仔细观察行为,附带病史和认知测试.
对于年轻的患者来说,自身免疫查是必不可少的,因为他们呈现出无法解释的血管病变和认知症状.

关键词:

漠不关心漠不关心痴呆症是一种痴呆症.早期发病的痴呆症是什么神经精神病学是一种神经精神病学.一次性中风,中风.系统性红斑性狼红斑性狼系统性狼血管痴呆症是一种精神疾病.

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