突触射击噪声会在平衡的神经网络中触发快速和缓慢的全球振荡
Denis S Goldobin1,2, Maria V Ageeva1, Matteo di Volo3
1Institute of Continuous Media Mechanics, Ural Branch of RAS, Acad. Korolev Street 1, 614013 Perm, Russia.
Physical review. E
|October 21, 2025
概括
这项研究引入了神经网络的新平均场理论,将突触射击噪声纳入其中,以揭示新的动态模式和通过扩散近似来预测不到的自我维持的振荡.
科学领域:
- 计算神经科学是一种神经科学.
- 理论神经科学 理论神经科学
- 神经动力学建模神经动力学建模
背景情况:
- 神经动力学依赖于突触脉冲传输 (突触射击噪声).
- 传统模型通常将突触输入作为连续的高斯噪声近似,限制了准确性.
- 现有的扩散近似无法捕捉复杂的神经网络行为.
研究的目的:
- 为稀疏,平衡的抑制性神经网络开发一个严格的平均场理论,以解释突触射击噪声.
- 为了识别和描述超出扩散近似的新动态模式.
- 探索神经网络中自我维持的全球振荡的出现和特性.
主要方法:
- 开发一个严格的平均场理论,结合突触射击噪声.
- 通过刺激输入驱动的稀疏平衡抑制神经网络的分析.
- 理论预测与数值模拟的比较.
主要成果:
- 该理论预测了其他动态模式,包括自我维持的全球振荡,而不是通过扩散近似来捕捉.
- 这些振荡通过连续或歇斯底里过渡在低连接性出现,以不规则的神经活动为特征.
- 一条回入过渡线揭示了低度和高度的振荡,由异步状态分开,具有不同的出现机制 (漂移驱动与集群激活).
结论:
- 突触射击噪声对于理解复杂的神经动态和出现的振荡至关重要.
- 开发的平均场理论为模拟神经网络提供了更准确的框架.
- 低度的集群激活振荡可能是哺乳动物皮层和海马体中观察到的马节奏的基础.
相关概念视频
Propagation of Action Potentials
8.9K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
8.9K
Integration of Synaptic Events
3.5K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...
3.5K
Synaptic Signaling
6.5K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
6.5K
Synaptic Signaling
79.1K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
79.1K
Neuronal Communication
3.0K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
3.0K
Neural Circuits
2.6K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
2.6K


