维生素D在术后肌愈合中的作用:一个范围审查
Marc Daniel Bouchard1, Danielle Dagher2, Carl Keogh3
1McMaster University, Division of Orthopaedic Surgery, Hamilton, Canada.
Orthopaedic journal of sports medicine
|October 21, 2025
概括
维生素D可能有助于肌愈合,特别是在旋转手腕受伤的情况下,但证据质量较低. 需要更多的研究来证实它在各种肌修复和指导补充中的作用.
科学领域:
- 整形外科 整形外科 整形外科
- 内分泌学 在内分泌学.
- 肌肉骨健康 肌肉骨健康
背景情况:
- 肌损伤由于血管性和生物力学不佳,造成愈合挑战.
- 尽管在手术和康复方面取得了进展,但仍然存在低于最佳的愈合率和高的遗弃率.
- 维生素D在肌肉骨健康中的作用表明它对肌修复有潜在的益处,但证据有限.
研究的目的:
- 对有关维生素D在肌愈合中的作用的现有文献进行范围审查.
- 评估维生素D对肌修复后术后恢复的影响.
- 测试维生素D缺乏与较差的愈合和更高的失败率相关的假设.
主要方法:
- 在Embase,OVID Medline和Emcare数据库中进行系统的文献搜索.
- 包括观察性研究和随机对照试验,研究肌修复的成年人维生素D状况.
- 由于研究异质性的结果的叙述综合,专注于证据差距.
主要成果:
- 包含了10项研究,主要涉及旋转手套修复 (80%).
- 维生素D缺乏与延迟愈合,更高的复发率和功能恢复的减少有关.
- 证据质量很低,大多数研究都是追溯的,有些依赖重叠的数据.
结论:
- 目前的证据表明,维生素D可能有助于肌愈合,特别是在旋转手套受伤的情况下.
- 低质量的研究和专注于一个肌组限制了最终的结论.
- 需要进一步进行高质量的前性研究,以确定因果关系并探索不同肌之间的影响.
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