诊断性能和潜在的危害,以人口为基础的食道胃管腺镜用于胃癌查
Hyoung Il Choi1, Jae Myung Cha1,2
1Department of Gastroenterology, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
Gut and liver
|October 21, 2025
概括
有效的食管胃腺镜 (EGD) 查胃癌更有可能检测到老年男性的高风险病变. 更高质量的程序指标,如更多的图像和更长的考试时间,也与检测相关. 这可以帮助完善查策略.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 基于人群的食道胃管腺镜 (EGD) 查胃癌需要评估诊断性能和危害.
- 国家癌症查计划使用EGD进行胃癌查.
研究的目的:
- 评估EGD用于胃癌查的诊断性能.
- 评估与EGD查相关的潜在危害.
- 为了比较中年和老年人之间的诊断产量和危害.
主要方法:
- 对40岁以上无症状个人进行了回顾性研究,他们接受了EGD查 (2017-2023年).
- 年龄组之间的诊断产量和危害的比较.
- 单变量和多变量波桑回归分析,以确定与高风险病变检测相关的因素.
主要成果:
- 癌前疾病 (64.3%) 和高危胃病变 (0.7%) 在老年人中更为普遍.
- 不良事件 (1.1%) 和假阳性结果 (2.8%) 在各年龄组中相似.
- 老年人 (3.4%) 的假阴性结果明显高于中年人 (1.1%).
- 高龄 (≥65岁),男性性别,更多的EGD图像和更长的手术时间与高风险的病变检测有关.
结论:
- 高龄,男性性别和程序质量指标独立地与基于人口的EGD查中的高风险胃病变检测有关.
- 结果可以为EGD计划的风险分层查策略和质量基准提供信息.
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