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基于或基于插头的关闭用于大孔动脉接入:对随机试验的个体患者水平元分析

Oliver Dumpies¹, Maarten van Wiechen², Alexander Jobs¹

¹Department of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

|October 21, 2025

概括

对于大孔动脉接入的ProGlide技术优于MANTA技术,显示出较少的血管和出血并发症. 这一发现有助于为患者选择最佳的血管闭塞装置.

科学领域:

干预心脏病学干预心脏病学
血管外科血管外科
医疗器械技术医疗器械技术

背景情况:

穿皮大孔动脉切除术的关闭采用基于或插头的设备.
对这些技术的比较有效性,安全性和患者选择仍在争论中.

研究的目的:

进行患者一级的元分析,比较ProGlide (基于接) 和MANTA (基于插头) 的大孔血管闭塞装置 (VCD).
评估与接入部位相关的血管并发症的主要终点.

主要方法:

系统搜索PubMed,控制试验的Cochrane中央注册表和谷歌学者相关的随机对照试验.
对比ProGlide和MANTAVCD的试验的患者级数据元分析.
接入部位相关的血管并发症根据Valve学术研究联盟-3标准定义.

主要成果:

通过ProGlide技术,血管并发症 (OR 0.54) 和出血事件 (OR 0.41) 的发生率显著降低.
小组分析没有发现基于插头的MANTA技术的任何优势.
在较大的船只中,MANTA技术显示出更好的结果,而ProGlide则减少了对后续干预的需求.

结论:

基于的ProGlide技术优于基于插头的MANTA技术,用于大孔动脉接入.
与MANTA相比,ProGlide与较少的血管和出血并发症有关.
这些发现支持ProGlide作为一种首选的VCD,用于减少大孔动脉接入程序中的并发症.

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