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Updated: Jan 14, 2026

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小 (≤4厘米) 清细胞细胞癌的风险因素和转移预测:一项嵌套病例对照研究

Zhiying Wu¹, Dameng Pan¹, Jinghui Ji¹

¹Department of Urology, Peking University Third Hospital, Beijing, 100083, China.

World journal of urology

|October 21, 2025

概括

小透明细胞癌 (ccRCC) 在4.7%的病例中会转移. 临床症状,较高的R.E.N.A.L. 分数,pT3阶段和高病理等级是转移的关键风险因素.

科学领域:

在瘤学瘤学.
泌尿器科泌尿器科泌尿器科泌尿器科
病理学病理学病理学

背景情况:

小透明细胞癌 (ccRCC) 是一种常见的癌亚型.
了解转移和预后因素对于患者管理至关重要.

研究的目的:

确定影响转移的临床病理因素和小ccRCC (≤4厘米) 的预后.
为指导小型ccRCC的临床治疗和术后管理决策.

主要方法:

对1054名小ccRCC患者数据 (2012-2024) 的回顾性分析.
嵌套病例对照研究,将50名转移性ccRCC患者与281名非转移性对照进行比较.
单变量和多变量逻辑回归分析以确定风险因素.

主要成果:

在小型ccRCC患者中观察到4.7%的转移率 (同步1.8%,超时2.9%).
非转移性ccRCC的五年总生存率为99.4%,转移性ccRCC为70.0%.
转移的独立风险因素包括临床症状,较高的R.E.N.A.L.L. 评分,pT3阶段,以及III/IV级病理分级.

结论:

小型ccRCC的转移潜力为4.7%.
临床症状,R.E.N.A.L. 的升高. 评分,pT3阶段和更高的病理等级是小ccRCC转移的重要风险因素.

关键词:

转移转移转移转移预测预后预测预测风险因素风险因素小型细胞癌是什么?

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