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在体外研究通过Kinsenoside对CAR-T功能的可逆调节

Guangmei Li1,2, Delian Zhou1,2, Shangwu Ning3

  • 1Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.

Molecular biology reports
|October 21, 2025
PubMed
概括

一种新型的天然化合物kinsenoside (KD) 作为一个功能开关,可以安全地控制化学抗原受体T细胞 (CAR-T) 疗法. 这一发现为平衡CAR-T疗效和管理毒性提供了一种新方法.

关键词:
汽车-T可逆调节规则效应器差异化的差异化免疫系统的平衡.这是一种昆塞诺化物.

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