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性取向,性别认同和心脏代谢风险:一个叙事审查
Meredith S Duncan1, Lauren B Beach2, Hill L Wolfe3
1Department of Biostatistics, University of Kentucky, Lexington, KY, USA.
Diabetologia
|October 21, 2025
概括
性别和性别少数群体 (SGM) 面临着不同的心脏代谢风险,包括糖尿病和心血管疾病. 更具包容性的研究对于理解和解决LGBTQ+个体的健康差异至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 健康差异 在健康上的差异
背景情况:
- 全球大约有9%的成年人认为自己是性和性别少数群体 (SGM),包括LGBTQ+个人.
- 在SGM人群中,有记录的健康差异,但心脏代谢风险,特别是糖尿病,仍未得到充分研究.
- 现有研究表明,在SGM亚群中,心脏代谢健康结果可能存在差异.
研究的目的:
- 审查SGM种群中心脏代谢风险因素和结果的流行病学.
- 专注于最近的元分析和大样本研究 (2017-2025年).
- 建议对SGM个体的代谢和心血管风险进行监测.
主要方法:
- 科学文献的叙述性审查.
- 专注于在2017年至2025年期间发表的元分析和大样本研究.
- 分析来自英国和美国来源的数据.
主要成果:
- 心脏代谢风险在SGM亚群和数据来源 (英国与美国) 之间有所不同.
- 性少数民族妇女在英国数据中显示糖尿病风险增加;跨性别成年人在英国和美国数据中显示糖尿病和心血管疾病风险增加.
- 慢性病 (CKD) 风险在英国SGM人群中较高,但与 cisgender,异性比较者相比,在美国人群中不一致.
结论:
- 对于SGM种群来说,心脏代谢健康存在显著差异,尽管根据亚种群和地理数据源的发现有所不同.
- 进一步的研究,包括包括SGM的纵向队列研究,对于准确地描述风险和开发有针对性的干预措施至关重要.
- 建议建议改善SGM个体心脏代谢健康的随访和监测.
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