时间性饮食模式和结肠直肠癌:系统性审查
Zegeye Abebe1,2, Molla Mesele Wassie3, Amy C Reynolds3
1Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, 5042, Australia. abeb0011@flinders.edu.au.
Current nutrition reports
|October 21, 2025
概括
饮食模式显著影响结肠直肠癌 (CRC) 风险. 在最后一顿饭和睡前之间的短时间间隔,以及更高的饮食频率,特别是不健康的食物,可能会增加CRC风险和死亡率.
科学领域:
- 营养科学 营养科学
- 胃肠病学 胃肠病学
- 癌症研究 癌症研究
背景情况:
- 已知饮食质量会影响结肠直肠癌 (CRC) 风险.
- 时间性饮食模式 (饮食频率,时间,规律性) 越来越多地被认为是潜在的CRC风险因素.
- 目前的饮食指南主要关注食品成分,而不是饮食时间,以预防CRC.
研究的目的:
- 系统地审查和综合有关时间性饮食模式与CRC风险之间的关系的证据.
- 探索食物的频率,持续时间,规律性和时间如何影响CRC风险和死亡率.
- 确定当前关于饮食模式和CRC的研究中的差距.
主要方法:
- 按照PRISMA指南进行系统的文献审查.
- 在Medline,Scopus,Web of Science,CINAHL和ProQuest数据库中进行的搜索.
- 收录了20篇相关文章,考察时间性饮食模式和CRC.
主要成果:
- 更高的饮食频率,特别是不健康的食物,与CRC风险增加有关.
- 跳过早餐和增加零食也可能增加CRC风险.
- 最后一顿饭和睡觉之间较短的间隔与更高的CRC风险和死亡率有关,可能是通过昼夜干扰,氧化应激和炎症.
结论:
- 时间性饮食模式在CRC风险和死亡率中起着重要作用.
- 具体的模式,如高的饮食频率和深夜饮食,需要进一步调查.
- 对于未来的研究,需要标准化定义和详细的24小时饮食评估.
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