分数:最可靠的指南建议什么? 使用G-TRUST工具进行分析
Yves-Marie Vincent1, Xavier Gocko2,3, Célia François4
1Department of General Practice, University of Bordeaux, Bordeaux 33000, France.
Family practice
|October 21, 2025
概括
可靠的临床实践指南 (CPG) 建议不要在初级预防中使用冠状动脉评分 (CSC) 来评估心血管风险. 然而,不太可靠的指导方针主张使用它.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 卫生政策 卫生政策
背景情况:
- 心血管疾病 (CVD) 仍然是全球主要的死亡原因.
- 临床实践指南 (CPG) 对使用冠状动脉评分 (CSC) 进行个人心血管风险评估提出了不同的建议.
- 由于缺乏共识,需要评估CPGs在初级预防中使用CSC的可靠性.
研究的目的:
- 评估CPGs关于CSC在心血管疾病初级预防中的使用的可靠性和相关性.
- 确定哪些CPG提供可靠的CSC利用风险分层的建议.
主要方法:
- 在PubMed的系统搜索中,确定了在2018-2023年期间发表的关于CSC在初级预防中的使用的CPG.
- 使用G-TRUST评估网格来评估所选择的CPG的质量和可靠性.
- 根据预先定义的标准,CPG被归类为"可靠和相关"或"不可使用".
主要成果:
- 在467份出版物中,只有7份CPG符合该研究的纳入标准.
- 在七个CPG中,只有两个被G-TRUST评估认为"可靠和相关".
- 其余的五个CPG被归类为"不可使用",原因是利益冲突,缺乏系统性审查或缺乏患者的意见.
结论:
- 这两个可靠的CPG得出结论,CSC不应用于初级预防中的心血管风险评估.
- 相反,被认为"不可使用"的五个CPG建议使用CSC.
- G-TRUST工具有效评估建议的方法质量,区分可靠的指南和不太可靠的指南.
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